
25 Best Mystery Anime of All Time(2026)
Mystery anime weave intricate puzzles, hidden truths, and suspenseful investigations. These series challenge viewers to piece together clues alongside brilliant detectives and uncover shocking revelations.

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Mystery anime weave intricate puzzles, hidden truths, and suspenseful investigations. These series challenge viewers to piece together clues alongside brilliant detectives and uncover shocking revelations.
In the American Old West, the world's greatest race is about to begin. Thousands line up in San Diego to travel over six thousand kilometers for a chance to win the grand prize of fifty million dollars. With the era of the horse reaching its end, contestants are allowed to use...

Using her wit and vast knowledge of medicines and poisons alike, Maomao played a pivotal role in solving a series of mysteries and conspiracies that plagued the imperial court. Having recently come to terms with the secrets of her parents, she returns to fulfill her normal...

Dr. Kenzou Tenma, an elite neurosurgeon recently engaged to his hospital director's daughter, is well on his way to ascending the hospital hierarchy. That is until one night, a seemingly small event changes Dr. Tenma's life forever. While preparing to perform surgery on someone,...

Following an encounter with oddity specialist Izuko Gaen, third-year high school student Koyomi Araragi wakes up in a strange, deserted void only to be greeted by a joyfully familiar face in an alarmingly unfamiliar place. Araragi, with the help of his girlfriend Hitagi...

After helping revive the legendary vampire Kiss-shot Acerola-orion Heart-under-blade, Koyomi Araragi has become a vampire himself and her servant. Kiss-shot is certain she can turn him back into a human, but only once regaining her full power. Araragi has hunted down the three...

Apparitions, oddities, and gods continue to manifest around Koyomi Araragi and his close-knit group of friends: Tsubasa Hanekawa, the group's modest genius; Shinobu Oshino, the resident doughnut-loving vampire; athletic deviant Suruga Kanbaru; bite-happy spirit Mayoi Hachikuji;...

Ghostly, primordial beings known as Mushi continue to cause mysterious changes in the lives of humans. The travelling Mushishi, Ginko, persists in trying to set right the strange and unsettling situations he encounters. Time loops, living shadows, and telepathy are among the...

It is said that a picture is worth a thousand words. In this case, it holds an infinite amount of secrets. These are secrets that only Cheng Xiaoshi and Lu Guang are able to find. In a small shop called "Time Photo Studio," the two friends provide a special service: using their...

Along an empty road in the rural countryside, Wei Wuxian and Lan Wangji stumble across a stone plaque that reads "Yi City." Still on their quest to unravel the mystery behind the cursed severed arm, they venture into the deserted city to obtain further leads. However, with the...

Eccentric and blunt, the walrus Hiroshi Odokawa lives a relatively normal life. He drives a taxi for a living, and there he meets several unique individuals: the jobless Taichi Kabasawa who is dead-set on going viral, the mysterious nurse Miho Shirakawa, the struggling comedic...

The Abyss—a gaping chasm stretching down into the depths of the earth, filled with mysterious creatures and relics from a time long past. How did it come to be? What lies at the bottom? Countless brave individuals, known as Divers, have sought to solve these mysteries of the...

The Armed Detective Agency is still on the run from the Hunting Dogs, but not all hope is lost. Detective Ranpo Edogawa has a plan to prove the Agency's innocence and save the world from chaos: to find and capture Kamui—the leader of the terrorist organization Decay of the...

In a Victorian world of steam, dreadnoughts, and occult horrors, Zhou Mingrui awakens as Klein Moretti. He walks a razor's edge between light and darkness, entangled with warring Churches. This is the legend of unlimited potential...and unspeakable danger. (Source: Crunchyroll)

On a cold December day, Kyon arrives at school prepared for another outing with his fellow SOS Brigade members. However, much to his surprise, he discovers that almost everything has changed completely: Haruhi Suzumiya and Itsuki Koizumi are nowhere to be found; Mikuru Asahina...

One autumn evening at a mysterious ramen stand behind the Shimogamo Shrine, a lonely third-year college student bumps into a man with an eggplant-shaped head who calls himself a god of matrimony. Meeting this man causes the student to reflect upon his past two years at...

Following the closure of the "Laughing Man" case, Section 9 is re-established by Japan's newly elected Prime Minister, Youko Kayabuki, to combat the persistent threat of cyber-terrorism. A group calling themselves "The Individual Eleven" has begun committing acts of terror...

In November 1998, a double homicide occurs at the newly constructed Ogawa apartment complex in the heart of Mifune City. The murderer, Tomoe Enjou, has fled in a panic. To his astonishment, he is not pursued by the police and news of the incident has not been reported through...

Surrounded by a forest and a gated entrance, the Grace Field House is inhabited by orphans happily living together as one big family, looked after by their "Mama," Isabella. Although they are required to take tests daily, the children are free to spend their time as they see...

Since the death of his parents, Shinpei Ajiro had lived with the Kofune family and their two daughters—Mio and Ushio. Although he then left his home island to continue his education in Tokyo, Shinpei returns after Ushio tragically drowns during the attempted rescue of a little...

A peculiar transfer student named Ougi Oshino has just arrived at Naoetsu Private High School. She is quickly introduced to senior student Koyomi Araragi by their mutual friend Kanbaru Suruga, in hopes of obtaining advice regarding a strange discovery she has made. After taking...

Gesicht, an android police detective of Europol, is tasked with finding the murderer of Montblanc, a retired war hero robot. Although it appears that only a robot could have committed this crime, the murder of a renowned robot rights activist casts doubts on the criminal's...

Graduation day is finally here, marking the end of Koyomi Araragi's eccentric high school life full of peculiar relationships with otherworldly beings. However, Araragi is unexpectedly absorbed into his own bathroom mirror and trapped inside a bizarre world where everything he...

Mysterious, unknowable creatures alien to the laws of nature—known only to some and feared by others—"Mushi" lie behind many of life's strange phenomena. Long ago, a Mushi of terrifying power threatened to extinguish all life. The Minai clan of Mushishi were born from those who...

The "Medicine Seller" is a deadly and mysterious master of the occult who travels across feudal Japan in search of malevolent spirits called "mononoke" to slay. When he locates one of these spirits, he cannot simply kill it; he must first learn its Form, its Truth, and its...

In order to protect the residents of Xiaoji Island and the peaceful life here, Wu Liuqi and his partners Dabao and Xiaofei embark on a journey to the Xuanwu Kingdom to find out the truth about his identity and a way to save the island. Waiting for them is more unknowns and...
Based on community ratings, Steel Ball Run: JoJo's Bizarre Adventure is the highest-rated mystery anime with a score of 9.21. In the American Old West, the world's greatest race is about to begin.
There are over 1,024 mystery anime tracked on AnimePulse, ranging from classic series to currently airing shows.
For newcomers to mystery anime, we recommend starting with Steel Ball Run: JoJo's Bizarre Adventure, The Apothecary Diaries Season 2, or Monster. These are widely loved by the community and serve as great entry points to the genre.