Shirayuki is a bright and resourceful girl, determined, able to speak her mind, and knowledgeable in both botany and medicine. Whenever there is a problem or conflict, she often takes matters into her own hands. She later learns to rely on others, especially Zen.
Due to her rare hair color, Shirayuki gets a proposal to be a concubine of the foolish but famous prince Raji. As she cannot decline it, she escapes to the neighboring country. While traveling, she meets a boy named Zen, who accidentally gets injured, and she boldly cures his wounds. They become friends, and she finds out than Zen is actually a prince of that country, and he saves her from being taken by Raji. They later go to his palace, where she applies for the job of "Palace Pharmacist," to be able to go freely to the castle where Zen is.
